Antibacterial Activity Of Moringa Stenopetala Against Some Human Pathogenic Bacterial Strains

An emerging of antibiotic resistance brings most serious public health problems. Itrnis therefore, important to look for more effective, safer and less toxic alternate options ofrntreatment. The aim of the present study was to investigate antibacterial activity of Moringarnstenopetala against some human pathogenic bacteria using disk diffusion method and agarrndilution for minimum inhibitory concentration. The result revealed that, most of the plantrnextracts had antibacterial activity. Staphylococcus aureus was found to be the most susceptiblernbacteria to crude 80% methanol extract of seeds and ethyl acetate extract of root barks withrninhibition zones of 18.66±0.88mm and 16.00±1.15mm and minimum inhibitory concentration ofrn1.25mg/ml and 2.5mg/ml respectively, whereas Pseudomonas aeruginosa was the most resistantrnbacteria to all of crude extracts. Similarly, Staphylococcus aureus was the most susceptiblernbacterial strain to chloroform fraction with inhibition diameter of 28.00±0.57mm and minimumrninhibitory concentration of 0.31mg/ml, while Pseudomonas aeruginosa was the most resistantrnstrain with inhibition zone of 9.66±0.33mm and minimum inhibitory concentration of10mg/mlrnrespectively. In conclusion, this study is not only proves antibacterial activity of Moringarnstenopetala, also provides a scientific basis for their traditional use. Pure chemical compoundsrnand antimicrobial activity against many fungi and bacteria should be studied to use them asrnsources and templates for synthesis of drugs to control infectious diseases.rnKey words and phrases: Antibacterial activity, Moringa stenopetala, traditional medicine,rnextracts, fractionation, MIC, solvents

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