Diarrhoea Associated Parasitic Infectious Agents In Patient S With Aids In Selected Addis Ababa Hospitals

The study was aimed at determining the prevalence of gastrointestinalrnparasites in AIDS patients with chronicrndiarrhoea. This prevalence was compared with that in tworncontrol groups: HIV seronegative diarrhoeal patients and AIDSrnpatients (HIV seropositive individuals) without diarrhoea.rnStool specimens were screened for parasite infection fromrnclinically diagnosed hospitalized AIDS patients in sevenrnhospitals in Addis Ababa. Of 147 AIDS patients with chronicrndiarrhoea, 74 (50.3%) were infected with one or more kind ofrnparasites. Out of the 56 non-AIDS (seronegative) diarrhoealrnpatients 23 (41.1%) and out of the 43 non-diarrhoealrn(seropositive) patients 18 (41.9%) were infected by a varietyrnof intestinal protozoa and helminths. The parasites detectedrnin AIDS patients only were crptosporidium spp, Isospora spp,rnand Blastocystis spp, Ascaris lumbricoides, Giardia lamblia,rnstrongyloides stercoralis, Taenia saginata, Trichurisrntrichura, Entamoeba histolytica, and Hook worm spp. Amongrnthe intestinal parasites, Cryptosporidium spp was exclusivelyrnassociated w.i th diarrhoeal AIDS patients (P < 0.001). None ofrnthe other parasites were significantly associated with AIDSrnpatients. The high proportion of the study subjects who hadrndiarrhoea in the absence of identifiable parasitic infectionsrnsuggests that other infectious agents (eg. Bacteria andrnVirus) or mechanisms other than infectious agents arernresponsible for the diarrhoea.

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