Perinatal Outcomes Of Pregnancies Complicated By Hypertensive Disorders Of Pregnancy In Late Preterm In Three Teaching Hospitals In Addis Ababa Ethiopia

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Background: Hypertensive disorders of pregnancy (HDP) are multisystem diseases known tornincrease the risk of perinatal mortality worldwide, with a significant proportion of these deathsrnoccurring in low income countries. However, little is known about the obstetric and treatmentrnpredictors of perinatal mortality in women with HDP. Until now, only few studies focused on thernmanagement of women with hypertensive disorders between 34 0/7 and 36 6/7 weeks ofrngestational age in Ethiopia. rnGeneral objective: To investigate the perinatal outcomes of late preterm pregnanciesrncomplicated by hypertensive disorders in low resource settings rnMethods: Hospital based cross sectional descriptive study was conducted on 274 newbornsrndelivered from December 15, 2020 to June 15, 2021 at the three teaching hospitals. Structuredrnand pretested questionnaire were used to collect socio-demographic data and medical recordsrnwere reviewed. Neonatal status was checked every other day through phone call till 7 days afterrndelivery date. Descriptive statistics were used to describe parameters collected from the files.rnBivariate and multiple logistic regressions were done to determine factors associated withrnunfavorable perinatal outcome. A P-value of less than 0.05 was considered statisticallyrnsignificant. rnResult: Among 10,129 deliveries during the study period, 952 (9.4%) were preterm. Of thesernpreterm deliveries 680 were late preterm and 274 neonates fulfill the inclusion criteria andrnanalyzed. About 83(30.3%) neonates were delivered 34+0-34+6 weeks, 45 (16.4%) at 35+035+6rnweeksrnandrnthernmajorityrnrn146 (53.3%) at 36+0-36+6 weeks. Cesarean section was the mostrncommon mode of delivery 191 (69.7%) followed by SVD, 74 (27%) and 6 (2.2%) by AVD. rnAbout 173 (63.1%) newborns were LBW (1500-2499 grams), 76 (27.8%) were NBW and thernremaining 25(9.1%) were VLBW. Fifty eight (21.5%) of neonates need resuscitations atrndelivery. Hundred forty eight (55.2%) of these neonates were referred to NICU and 102 (68.9%)rnof them required NICU admission. On day seven neonatal assessment the cumulative survivalrnwas 93.7%. The survival rate of late preterm neonates is 87.7%, 90.9% and 97.9% at 34, 35, andrn36 weeks respectively. The perinatal mortality rate in late preterm pregnancy in hypertensiverndisorders of pregnancy in this study was 76.6/1000 live births. Over half, 9/17 (52.9%) ofrnneonatal deaths occurs within the first 48 hours while majority (76.5%) of neonatal deaths occurs rnwith in the first 3 days. In this study one fourth (25.9%) of women had at list one maternalrncomplication. Fetal weight at birth, gestational age during delivery and Apgar score at deliveryrnfound to be independent predictors of perinatal survival. rn Conclusion and Recommendation: During the study period the rate of late preterm birth wasrn71.4%. This study shows preeclampsia as the most common cause for late preterm birth (84.7%)rnfrom hypertensive disorders of pregnancy. Late preterm neonates are at higher risk for neonatalrnmorbidities and mortality contrary to the belief that they are nearly mature. Neonatal birth weightrnand Apgar score during delivery were the important predictors for the neonatal survival. Criticalrnattention should be paid on the first 72 hours of newborn life to reduce factors contributing tornhigh neonatal loss at this particular time.

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Perinatal Outcomes Of Pregnancies Complicated By Hypertensive Disorders Of Pregnancy In Late Preterm In Three Teaching Hospitals In Addis Ababa Ethiopia

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