Background:Anemia is a common clinical problem contributing to increased maternal and fetalmorbidityand mortality during pregnancy. Anemia can be caused bydifferent factors apart fromknown diseases. The main aim of this study is to identify determinants of anemia amongpregnant women attending antenatal care at the public health facilities of GMH,ZMH andALERT hospitalsrnObjective:-This studyaims to assess the determinantfactors of anemia among pregnant womenattending Antenatal Care (ANC) in three selected public hospitals (GMH, ZMH and ALERThospitals), Addis AbabaEthiopia,case-control study.rnMethods:-A health facility-basedunmatchedcasecontrolstudydesign wasapplied, among 126cases and 252 controls from JAN,2021-APRIL, 2021G.C in three public hospitals in A.A,Ethiopia. Data were collected using interviewer-administered questionnaires. Controls werepregnant ladieswhosehemoglobinlevel was 11 g/dl and above at their first antenatal care clinic,and cases were pregnant ladies whose hemoglobin level less than 11 g/dl in the first and 3rdtrimester and 10.5g/dl in the second trimester.collected data were entered using SPSS version 25for analysis. First Bi-variable logistic regressions were used to find out determinant factors ofanemia at P–value≤ 0.025, and thenmultivariable logistic regressions were used to control outconfounding variables. Adjusted odds ratio (AOR) with 95% confidence interval (CI) and p-value