Abstract rnSoft tissue sarcomas are an uncommon group of neoplasm that could be fatal, especially in the metastaticrnsetting. rnLate presentation, Missed Diagnosis and inadequate treatment may worsen clinical outcomes. rnThere is lack of evidence on the demographic, pathological, Clinical and treatment pattern of soft tissuernsarcoma in developing countries like EthiopiarnThus, this study is aimed to assess the demographic, pathological, Clinical and treatment patterns of soft tissuernsarcoma in a single tertiary health institution in Ethiopia. rn rnObjective: rnThe aim of this study is to assess demographic, pathologic, clinical and treatment pattern of soft tissue sarcomarnat Tikur Anbesa Specialized hospital at four years duration. rn rnMethods rnThis is a retrospective cross-sectional study that asses demographic, clinical,pathologic and treatment pattern ofrnsoft tissue sarcoma at the TASH between august 2017 and August 2021 G.C. This period was selected becausernmost patient data before this are not available according to my pilot study. rnResult: rnA total of 320 patients were registered from August 2017 to August 2021 and 190 patients card were available for thisrnstudy and 80 of patients were excluded according to exclusion criteria and 50 of patientsâ€™ card were lost. The median age rnwas 32 years of age and Male sex was commonly affected accounting 61.6% and female sex accounts 38.4%.rnThe commonest sites were extremities accounting for 48.9 % of cases. The Commonest presenting symptomsrnwere mass and pain accounting for 93.2% and 77.9% of cases respectively. rnThe commonest histology subtypes were, undifferentiated sarcoma, rhabdomyosarcoma and synovial sarcomarnaccounting 50%, 15.8% and 6.3 % cases respectively.rn The grade of the lesions was described in 67.3 % of patients. Of those lesions whose grade was described 56.8rn% were high grade lesions. rnFrom all cases 58.3% of the patients underwent surgery as a primary treatment modality. Only 50.5% of casesrnwere started treatment with curative intent and 49.5% of the case started their treatment with palliative intent. rnConclusion: rnThe pattern of soft tissue sarcoma in this cross sectional study has shown different distribution in terms ofrndemography, clinical presentation, treatment and pathological subtypes when compared to other studies.rnAdvanced stage of initial clinical presentation and substandard work up according to standard text books andrntherapy makes it unique from cases reported from other parts of the world