Background Anemia is a global public health problem which has severe impact on pregnantrnmother. Anemia in pregnant women has severe negative consequences on health, social, andrneconomic development which result in at risk of low physical activity, increased maternalrnmorbidity and mortality and adverse neonatal outcome especially those with severe anemia..rnDespite the wider scope of the problem, little research data has been explored about severity ofrnanemia at ANC in study area particular, which resulted from secondary to underlying factor likernplant base consumption (goder), lack of awareness about iron/folic supplementations benefits,rnabsence of early antenatal booking, lack of dietary diversity and intake of fluid (chemo) thatrnhinder iron /folic absorption.rnObjective The study aimed to assess Prevalence of anemia and associated risk factors amongrnpregnant women attending antenatal carernat Mizan Tepi Teaching Hospital in South westrnEthiopia from March to April, 2016rnMethods Facility based cross-sectional study design was conducted from March to April, 2016rnon 405 pregnant women. Study subject were selectedrnconsecutivelyrnduring data collectionrnperiod time until the sample size were fulfilled at ANC clinic. Data were entered in to Epi Infornversion 3.5.3 and analyzed using SPSS version 21 statistical software. The significantlyrnindependent value of the variable to Anemia were identified by bivariate and multiple logisticrnregression analysis. Finally, results were presented in texts, graphs and tables.rnResult The overall prevalence of anemia among pregnant women was 41.2%. Meal frequencyrnless than two per day (AOR=3.166, CI [1.2601, 7.956]), third trimester (AOR=8.040, CI [3.201,rn20.196]), excess menstrual bleeding (AOR=5.403, CI [3.027, 9.644]) and intake of tea alwaysrnafter meal (AOR = 3.73, CI [2.060-6.780]), were factors significantly associated with anemia.rnConclusion This study showed that anemia is a moderate public health problem. The presentrnstudy had shown a statistically significant association between anemia and increased gestationalrnage, meal frequency less than two per day, excess menstrual bleeding, and tea intake after meal.rnAwareness creation through the strengthened health education on risk factors like avoiding tearnintake after meal and prevention of anemia as well as nutritional counseling should highlyrnrecommended during ANC follow up in an attempt to reduce the prevalence of anemia amongrnpregnant mothers.rnKeywordrnprevalence, associated factor, anemia pregnant women