Background: Cervical cancer remains a major cause of morbidity and mortality among womenrnin the world. It has been estimated that about 500,000 cases of cervical cancer occur worldwidernyearly, with 85% occurrence in resource-poor countries. In Ethiopia, cervical cancer is the 2ndrnmost common female cancer in women aged 15 to 44 years and 7,095 new cervical cancer casesrnare diagnosed annually. The most common factors which contribute for cervical cancer and itsrnprevention are: inadequate knowledge about the disease, early initiation of sexual intercourse andrnmultiple sexual partner. Therefore; basic knowledge and an early screening for cervical cancer isrna key intervention in reduction of maternal deaths secondary to cervical cancer.rnObjectives: To assess the knowledge, attitude, practice of cervical cancer screening and itsrnassociated factors among female students in Hawassa University College of Medicine and HealthrnSciences, Hawassa Ethiopia 2015.rnMethods: A cross sectional quantitative survey was conducted using a pretested anonymous self-rnadministered questionnaire among female students in Hawassa University College of Medicinernand Health Sciences from January, 2015 to May 30. The study subjects were selected using byrnlottery method of simple random sampling technique and a total of 422 female students aged 18-rn26 years took part in the study. Six diploma midwives were employed to facilitate data collection.rnThe collected data were entered in using EPI-info version 3.5.1 software and exported to SPSSrnversion 20 for further analysis. Bivariate and multivariate logistic regression analysis wasrnconducted to examine the factors associated with knowledge, attitude and practice towardsrncervical cancer screening. For data processing and analysis, SPSS version 20 was usedrnResults: overall, (76.8%) of the female students had heard about cervical cancer. Risk factorsrnlike having multiple sexual partners and initiation of sexual intercourse at early age by and Humanrnpapilloma virus were mainly reported risk factors for cervical cancer by 189 (49.7%) and 47.4%rnof respondents respectively. Of the risk factors, 189 (49.77% ) of students indicated that havingrnmultiple sexual partners and initiation of sexual intercourse at early age were commonly reportedrnrisk factor for cervical cancer while 180(47.4%) of them identified Human papilloma virusrnBut only 202(53.3%) of the respondents were heard about cervical cancer screening, and almostrnnear to half 48.2 of the respondent were not knew whether there is screening procedures to detectrnearly stages of cervical cancer. There were poor practice of cervical cancer screening amongrnfemale students. Also almost near to half 170(44.7%) of the students had negative attitude towardsrnscreening practice.rnConclusion: More than half of the respondents knew about risk factors and symptoms of cervicalrncancer fairly and most of the students heard about cervical cancer. But most of the respondentsrnwere not heard weather there is screening methods for early detection of cervical cancer and poorrnpractice of screening.rnKeywords:rnCervical cancer, Cervical cancer screening, Knowledge, Attitude, Practice