Survival Status And Predictors Of Mortally Among Preterm Neonates Admitted To Neonatal Intensive Care Unit Of Addis Ababa Public Hospitals Ethiopia 2021.

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Background: Preterm neonates have much greater risk of death and disability compared withrnterm neonates due to immature organ system which makes them unable to tolerate the extrarnuterine environment. In Ethiopia almost 90% of neonatal deaths are due to three preventablerncauses among which preterm complications are the one. The country accepts initiatives torndecrease preterm mortality and much is already being done to decrease mortality related tornpreterm complications. But studies about time to death in prospective design are limited. rnObjective: The main aim of this study is to determine survival status and predictors of mortalityrnamong preterm neonates admitted to public hospitals in Addis Ababa, 2021. rnMethodology: An institutional based prospective follow up study was conducted among 358rnpreterm neonates admitted to selected public hospitals in Addis Ababa, Ethiopia from Februaryrn12 to May 12, 2021. Ethical approval was obtained from Institutional Review Board (IRB)rnAAU, CHS. Data was collected prospectively using structured questioner which was adaptedrnfrom previous literatures. Data was entered into Epi Data version 4.6 and exported to STATArnversion 14 for analysis. Descriptive statics to describe variables, the Kaplan Meier failurernestimate curve to estimate the cumulative time to death and Log rank tests were used to comparernprobability of hazard between different categories. Bi-variable and multi-variable Coxrnproportional hazards models were used to identify predictor variables and variables having prnvalue < 0.05 were considered as statistically significant.rnResult: At the end of this cohort, 125(34.9%) of the neonates died, with incidence rate ofrn36.4/1000 person-day. The first 7days after admission was the hazard time to death in whichrn105(84%) of preterm neonates died. Being born to APH mother (AHR: 3.1, CI; 1.4-6.6), lackrnof KMC (AHR: 5.8, CI; 2.37-14.33), unable to start feeding with in 24hours of admission (AHR:rn6.4, CI: 3.33 -12.28), apnea (AHR: 2.4, CI: 1.3-4.7) and dehydration during the follow up periodrn(AHR: 2.33, CI: 1.3-4.3), were identified predictors of time to death. rnConclusion and Recommendation: The proportion of preterm death in this study was highrncompared to the pervious study conducted in Tikur Anbesa Specialized Hospital. Being born tornAPH mother, lack of Kangaroo Mother Care, unable to start feeding with 24hour, Apnea andrndehydration were the predictors’ time to death. Therefore, intervention that focuses on thernidentified predictors could have a paramount effect in reducing preterm death.

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Survival Status And Predictors Of Mortally Among Preterm Neonates Admitted To Neonatal Intensive Care Unit Of Addis Ababa Public Hospitals Ethiopia 2021.

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