Survival And Predictors Of Asphyxia Among Neonates Admitted In Neonatal Intensive Care Units Of Public Hospitals Addis Ababa Ethiopia 2021.

Background: Perinatal Asphyxia is an injury that occurs during the perinatal period due tornlack of oxygen flow to the fetus or infant, which may lead to ischemia of the brain or otherrnorgans. Gathering current evidence on recovery time and survival predictors of perinatalrnasphyxia is crucial to fill scarcity of information. rnObjective: To assess survival and predictors of asphyxia among neonates admitted inrnNeonatal Intensive Care Units of public hospitals, Addis Ababa, Ethiopia, 2021. rnMethods: Hospital-based retrospective cohort study was conducted in four selected publicrnhospitals of Addis Ababa, Ethiopia. Data were collected from February 15 to 15 March, 2021rnby reviewing medical charts of asphyxiated neonates who were registered from January 1,rn2016, to December 31, 2020. Epi data version 4.6 was used for data coding, entering and usedrnSTATA version 16 statistical software for further analysis. Cox-proportional hazardsrnregression analysis with 95% confidence interval and P-value < 0.05 level of significance wasrnused to verify predictors of survival of Perinatal Asphyxia. rnResult: In this study, out of 411(94.5%) participants, 305(74.2%) of them survived during thernentire cohort. Overall incidence density rate of survival was found to be 10 (95% CI: 0.080.11)rnrnper 100 neonate-days of observation with an overall median recovery time of 8 days.rnNeonates those who have low birth weight (AHR: 0.67, 95% CI: 0.47- 0.96), stage II HIErn(AHR: 0.70, 95% CI: 0.51 - 0.97), stage III HIE (AHR: 0.44, 95% CI: 0.27 - 0.71), occurrencernof seizure (AHR: 0.61, 95% CI: 0.38 - 0.97), thrombocytopenia (AHR: 0.44, 95% CI: 0.24 -rn0.80) and not supplied calcium gluconate within first days of life after birth (AHR: 0.75, 95%rnCI: 0.58 - 0.99) were independent predictors of time to recovery of asphyxiated neonates. rnConclusion: In this study, recovery time was prolonged in any stages of HIE compared tornSaranat’s staging of HIE. This implies early prevention, strict monitoring and takingrnappropriate measures timely is mandatory before babies transferred into highest stage of HIErnfor satisfactory outcomes and reduce mortality.

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