A wide range of medicines and other pharmaceutical products are needed for diagnosis,rntreatment, care, and prevention of HIV/AIDS. However, interrupted supplies and stock outs arernthe major challenges in the supply chain of ARV drugs. Therefor the aim of this study was tornassess the supply chain management of HIV/AIDS related commodities at hospital and HCsrnlevel in Addis Ababa, Ethiopia. A descriptive cross sectional survey complemented byrnqualitative approach was conducted in 24 government owned health facilities (4 hospitals and 20rnhealth centers) that provide ART, VCT and PMTCT service in Addis Ababa. The sample ofrnhealth facilities were calculated by using the Logistic Indicators Assessment Tool (LIAT) forrnARV drugs and Test kits developed by USAID/DELIVER. The data was collected r using semistructuredrnquestionnaires and observation check lists. The study revealed that 16(80%) of HealthrnCenter and 1(25%) of hospital pharmacies properly report and have the record of patients byrnregimen data. Almost all facilities had Electronic Dispensing Tool and used it for recordingrnpatient information on daily bases. Only, 14(70%) of the Health Centers used paper based ARVrndrugs dispensing register as a backup. Six months prior to the study, 14(70%) of Health Centersrnand 2(50%) of the hospitals stopped VCT service due to lack of adequate supply. The majority ofrnthe hospitals 3(75%) and 18(94.7%) of Health Centers were able to submit the requisition andrnreport of ARV drugs to Pharmaceutical Fund and Supply Agency according to the schedule.rnMore than three- fourth of the Health Centers had one or more emergency order of ARV drugs,rnwhile all of hospitals had emergency order more than 3 times within 6 months prior to the study.rnAll of the hospitals and nearly half of the Health Centers had an emergency order of test kitsrnmore than 3 times in the past 6 months. The mean percentage difference between quantityrnordered and received was high for 3TC300/TDF300 (69.6% in hospitals and 51.7% in HCs).rnOver all 14(73.7 %) of the Health Centers and 3(75%) of the hospitals faced stock out of one orrnmore ARV drugs on the day of visit. Stock out was high for nvp200 in hospital 2(50%) and itrnwas high for tdf300/3tc300 in HCs 7(36.8%). Regarding the stock status of test kits on the day ofrnvisit; only 7(36.8%) of the HCs were fully stocked, while the rest of them were stock out of onernor more selected test kits. Whereas, all of the hospitals were stock out one or more test kits onrnthe day of visit. Unlike ARV drugs, only 10(52.6%) of HCs and 2(50%) of hospitals had bin cardrnfor the selected test kits on the day of visit. All of the health facilities used both computerizedrniirnand paper based LMIS; they used computerized electronic dispensing tool at dispensary andrnHealth Commodities Management Information System in the store. The study concludes thatrnthere was not adequate data on patient by regimen and stock status of ARV drugs and Test kits.rnThere were frequent stock outs of ARV drugs and HIV test kits, which are an indicator of weakrnsupply chain. The reporting and receiving system of ARV drugs were more organized comparedrnto HIV test kits. It was also noted that in majority of the cases the professionals were unable tornhandle the computerized LMIS, as desired. It was recommended for the hospitals and healthrncenter handling HIV/AIDS related commodities to have adequate and reliable patientrninformation and drug utilization data on hand and improve their storage conditions and preventrnexpiry and wastage of expensive ARV drugs and HIV test kits.rnKey words: HIV/AIDS, ARV drugs, HIV test kits, supply chain Management, pharmaceuticalrnstorage