Medical equipment are essential for a functioning health system. Medical equipment inrnparticular are crucial in the prevention, diagnosis, and treatment of illness and disease, as wellrnas patient rehabilitation. The objective of this study is to analyse the medical equipment supplyrnchain management of public hospitals under Addis Ababa Regional Health Bureau. Bothrnquantitative and qualitative approaches are used in an explanatory and descriptive researchrndesign. A total of 339 samples were taken from 2231 population. Across sectional data wasrncollected using Simple random sampling and purposive sampling methods for quantitative andrnqualitative data collection respectively. Structured questionnaires and open ended interviewrnquestions are used as a tool for data collection. The data were analysed using both descriptivernand inferential statistical tools. Moreover, the result was described using mean, frequency andrnstandard deviation, and the researcher was also applied parametric statistical testrn(correlations, and regression analysis (Simple, multiple)) to interpret and analyze the data,rnusing Statistical Package for Social Science version 21.The findings showed that the efficiencyrnof medical equipment supply chain management in public hospitals is found to be stronglyrnaffected by the procurement, inventory, transportation and warehouse management practices.rnMajority of respondents disagree for having good procurement, inventory, transportation andrnwarehouse management in public hospitals under Addis Ababa Regional Health Bureau. Fromrnthe overall findings we can conclude that medical equipment supply chain managementrnpractices of public hospitals under Addis Ababa Regional Health Bureau is inefficient whichrnwill contribute for not giving quality health service. This is mainly due to poor practices in thernprocurement, inventory, transportation and warehouse management. From the findings of thernstudy 44.5 percent of the variance in efficiency of medical equipment supply chain wasrnexplained by the variance of explanatory variables, while the rest 55.5 percent was contributedrnby other factors that were not included in the model. Hence it is recommended that FederalrnMinistry of Health should work for improving of medical equipment supply chain managementrnpractices of facilities such as to prepare updated medical equipment list nationally and at eachrnlevel of the facility, to develop health commodities procurement policy. Addis Ababa regionalrnhealth bureau together with hospital management and staffs should give attention and workrncooperatively to improve the practices of medical equipment supply chain management ofrnhospitals.