Prevalence Of Antipsychotic Induced Movement Disorders Among Schizophrenia Patients At Amanuel Mental Specialized Hospital Addis Ababa Ethiopia.

Introduction: Despite an increasing number of studies identifying the prevalence ofrnantipsychotic induced movement disorders among schizophrenia patients in high income rncountries, limited reports on prevalence of this disorder who were visited health facilities hasrnbeen published in Ethiopia among patients who were treated with antipsychotics and all studiesrnwere focused on first generation antipsychotics. rnObjective: To determine the prevalence of antipsychotic induced movement disorders, andrnassociated factors among schizophrenia outpatients at Amanuel Mental Specialized Hospital. rnMethods:Data was obtained from the baseline assessment of the clinical trial placebocontrolledrnrntrial of folate with B12 in schizophrenia patients with residual symptoms conducted rnfrom 2014 to 2017 at Amanuel Mental Specialized Hospital. A total of 200 outpatients who wererntaking antipsychotics for at least six months or stable at least for six weeks were recruited in thernstudy. Rating scales were used including Abnormal Involuntary Movement Scale (AIMS) forrnTardive dyskinesia (TD), the Simpson-Angus Rating Scale (SAS) for Antipsychotic-InducedrnParkinsonism and Barnes Rating Scale (BAS) for Akathisia. The minimum threshold value forrnthe diagnosis of TD was a score of ≥2 on AIMS; for Parkinsonism, SAS mean global score ofrn≥0.65 and for Akathisia a BAS total score of ≥2. Positive and negative syndrome scale (PANSS)rnand scale for assessment of negative symptoms (SANS) were used to measure symptom severityrnof schizophrenia as mildly ill 58, moderate 75, marked 95 and severe 116 and at least moderate rnone is taken. rnData analysis was conducted using SPSS version 24.0. Frequency and percentage were used tornsummarize the data, tables and graphs were used to present the data. Binary logistic regressionrnwas done to see the association between the outcome variable and explanatory variables. Thern95% confidence interval was used and significance value P

Get Full Work

Report copyright infringement or plagiarism