Background: Throughout the world, work related injuries continue to cause serious publicrnhealth problems and are leading cause of death, disability and disease. In developing countriesrnincluding Ethiopia, the risk of having work related injury is 10 to 20 times higher than that ofrndeveloped countries.rnObjectives: This study investigated the magnitude and extent of work-related injuries amongrnsmall and medium scale industrial workers in Gondar Woreda.rnMethods: Stratified random sampling technique was employed to identify the industries. Arntotal of 962 workers at production site were interviewed from both industries. Three hundredrntwenty one from small and 641 from medium scale industries were selected proportionate tornpopulation size. Workers from each industry were selected using simple random samplingrntechnique. Trained data collectors administered a standardized questionnaire through face- tofacerninterview. Physical examination, record review and workplace observation were done tornascertain the self- reported information. Data were analysed by stepwise binary logisticrnregression model.rnResults: The over all annual prevalence rate of work related injury was 335/1000 exposedrnworkers, with 355/1000 and 324/1000 among small and medium sale industrial workers,rnrespectively. Fifty five (17.1%) of the injured respondents were hospitalised, accounting forrn40% hospitalisation more than 24 hours. One hundred and three (53.9%) of the injuredrnrespondents were absent from work for more than 3 days. There were 2 deaths as result ofrnwork related injuries in the last 12 months. The significant contributing factors for workrnrelated injuries in both industries were young age(