Background: The sexual behavior of HIV infected people has received little seriousrnattention for a range of factors. Even though many of them avoid risky sexualrnbehavior, a substantial number continue to engage in risky sexual practices thatrnnot only transmit the virus to others but also place themselves at risk of contractingrnsecondary infection.rnObjective: This study aimed to assess risky sexual practice and factors relatedrnamong people living with HIV/AIDS (PLWHA) attending ART in Addis Ababa publicrnhospitalsrnMethods: A cross-sectional quantitative study supplemented with a qualitativernstudy was conducted among ART attendants in Addis Ababa public hospitalsrnfrom February to March, 2009.rnResults: The majority of the respondents were using condoms consistently;rnhowever, significant proportion (36.9%) had a history of unprotected sex in thernthree months prior to the study period. The major reasons given for not usingrncondoms were partnerâ€™s dislike of them, both partners being positive for HIV andrnneed to have a child. Discussion about condom use and safe sex (AOR=7.23,95%rnCI: 4.14, 12.63), negative safer sex pleasure (AOR=2.39, 95% CI: 1.52, 3.76), multiplernpartnerships (AOR=2.67,95% CI:1.09, 6.57), negative partner serostatus (AOR=0.33,rn95% CI:0.14,0.80), unknown partner serostatus (AOR=0.19 CI 95% CI: 0.09,0.39) andrnself-efficacy to use condom ( AOR =3.29, 95% CI: 2.07, 5.23) are factors associatedrnwith unprotected sex.rnConclusion and Recommendation: Even if majority of ART attendants usedrncondoms consistently, still considerable number engaged in unprotected sex withrnHIV positive, negative or unknown serostatus partner. This would have negativernixrneffect in terms of reinfection with a new strain, other sexually transmitted infectionsrnand further transmission of the virus. So, interventions targeted to those factorsrnrelated with unprotected sex practice were recommended to be addressedrnthrough counseling, teaching, encouragements and other possible approaches