Background: - Knowledge, attitude and practice gaps are among the main challenges inrnproviding quality basic health services to the urban community. This can be among the reasonsrnfor low tuberculosis case detection by urban health extension professionals. Identifyingrnknowledge, attitude and practice gaps and associated factors, and taking active measures towardsrnthe gaps could improve tuberculosis case detection.rnObjective: - To assess the level of knowledge, attitude and practice of urban health extensionrnprofessionals towards tuberculosis case detection and associated factors in Addis Ababa,rnEthiopia.rnMethods: - A cross-sectional study design was used from April to May 2019 in randomlyrnselected four sub-cities in Addis Ababa, Ethiopia. Data was collected from 402 study participantsrnusing structured questionnaire. Epi info version 7 was used for data entry and SPSS version 20rnsoftware for data analyses. To identify variables which have significant association with thernoutcome variables, multivariable logistic regression analysis was performed. The statisticalrnsignificant was determined by adjusted odds ratio with 95% confidence interval.rnResult: - This study showed that 56.2 of the respondents have good knowledge, 58.5% goodrnattitude and 52% good practice towards tuberculosis case detection. Age group of 25-34 yearsrnold and frequency of supportive supervision on weekly basis are significantly associated withrngood knowledge with p-value of 0.008[AOR=2.487, (95% CI =1.265-4.888)] and p-value ofrn0.006[AOR=2.911, (95% CI=1.361-6.225)] respectively. Similarly getting referral feedbacksrnfrom the catchment health centres is significantly associated with the good practice of the studyrnrespondents with p-value of 0.001[AOR=3.526, (95% CI=1.665-7.467).rnConclusion: - This study reveals that half of the urban health extension professionals have arngood knowledge, attitude and practice which is relatively not satisfactory to provide good qualityrnservices to the urban community. Interventions that boost the knowledge, attitude and practicernlevel of them should be implemented including frequent supportive supervision, providingrnreferral feedback timely from the health centers and engaging family members in supportingrntuberculosis patients.