Background: - Routine Health information system (RHIS) is a system whereby health data rnare recorded, stored, retrieved, and processed to improve decision-making in the healthrnsector. Reliable and timely available health information is vital for operational and strategicrndecision making that saves lives and enhances health. In Ethiopia, information availabilityrnand use remain weak among health professionals, particularly at district health offices andrnprimary health care facilities to facilitate decision making, even in Addis Ababa. There isrnpoor access to health information use at the facility level. Poor handling of medicalrndocumentations among health professionals is an additional burden for the health carernsystem. rnHence, this study aimed to assess the information utilization status of Routine HealthrnInformation System and associated factors among health professionals in Addis Ababa cityrnpublic health centers. rnMethod: - Facility-based cross-sectional study design was conducted from March to Aprilrn2020 among 408 health professionals randomly selected from 22 health centers in AddisrnAbaba. Data collected using a Semi-structure questionnaire and an observational checklistrnwere cleaned, coded, and entered into EpiData version 3.1 and transferred into SPSS versionrn20 for further statistical analysis. Descriptive statistics like frequencies, proportions, andrnsummary statistics were used to summarize key findings. Variables with a p-value of lessrnthan 0.05 at multiple logistic regression analysis were considered statistically significantrnfactors for the utilization of Routine health information system. Odds ratios with 95%rnconfidence interval were computed to identify the factors statistically associated with routinernhealth information use. rnResult: - a total of 402 respondents have participated in the study with a response rate ofrn98.5%. The median age of study participants was 29 with IQR of 29. Of the total, 103rn(25.6%) had attended RHIS related training. Good Routine health information utilization raternamong health professionals was 37.3% (95% CI: 32.6%, 42.1%). Use of both manual paperrnfiles and computer-based files for recording information[AOR= 1.474 95% CI (1.043, 2.082)]rnat p-value 0.028, Organizational rules, values and practices [AOR= 1.734 95% CI (1.212,rn2.481)] at p-value 0.003, Inadequate Human resource [AOR= 1.494 95% CI (1.056, 2.114)]rnat p-value 0.023, Problem solving skill of health professionals on HIS tasks [AOR= 2.091rn95% CI (1.343, 3.256)] at p-value 0.001, Belief on routine health information use [AOR= 0.665 95% CI (.501, .883)] at p-value 0.005, the Collected information used for planning,rnmonitoring and evaluating of facility performance [AOR= 1.464 95% CI (1.006, 2.131)] at pvaluern0.046rnandrnKnowrntheirrndutiesrnandrnresponsibilitiesrninrntheirrnworkrnplacern[AOR=rn1.525rn95%rnrnCIrnrn(1.121, 2.073)] at p-value 0.007 are significantly associated with routine healthrninformation use. rnConclusion: - Good health information utilization status of health professionals in this studyrnwas low. Major skill gaps present in the studied health centers health professionals regardingrninformation use. Besides, there is a low level of data collection, data management,rninformation generation, and use that needed for the decision-making process and patientrnservice delivery. Routine health information use was better exercised among healthrnprofessionals who practiced both paper and computer-based information handling, those whornhave well organized Organizational rules, values and practices, those who collected and usedrninformation for planning and monitoring facility performance, those who have adequaternhuman resource, those who have good problem solving skill, those who had positive belief onrnRHIS use and those who Know their duties and responsibilities in their work place. Thus,rnmajor improvements have to be done in equipping health professionals to generate and utilizernthe information they have.