Malnutrition And Measles Ig. G. Elisa In 0-23 Months Children Comparison Of Seroconversion And Vaccine Side Effects Addis Ababa

A cohort of 9 23 mo nths old Addis Ababa childrenrnwere assessed as to their immune response to meas l esrnvaccine in relation to their nutriti o nal status. Of the 307rnpairs of blood spec imens analyzed for meas les antibody, 207rn( 67.4 %)rn(32.6%)rnhadrnhadrna negati ve preva c einiltion tit er while 10 0rnprevaccination titers th a t we r e s e rop os iti~ e.rnAm 0 n g the s e ron ega t i ve s a 95% s e ro c 0 n "e r s ion rat e wasrnobtained with no difference b et"r>en the malnourished andrnwell n o urish e d. Ther!' Has n o differen ce in side e ffe ctsrnrepo rt e d to th e meas l es vaccin e betwe!'n well n ou ri shed andrnmaln o urished c hildr e n. raccination of thos e wh o werernseropositive at th e outset didn't r esults in an), boosterrne f f e c t, de fin e d by a f 0 u r f 0 I d r i s e fr o m the pre - i 0 U srntite r'. Only 9 (9%) o f these ch ildr e n showed a boosterrneffect. A va lidity test f or his to r y of measles aga inst thernlaboratory results gave a 9 5. 1% specificity and 3 1%rnsensitivity rat e . A secon

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