Imaging And Histopathologic Correlation Of Pediatricoculo- Orbital Tumors Evaluated In A Tertiary Level Teaching Hospital In Ethiopia Three Years Retrospective Study

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Objective: This study is conducted to assess the cross sectional (CT and MRI) imagingrnpattern of pediatricoculo-orbital tumors and correlate with histopathologic finding and therernis also general discussion on sociodemographic characteristics and clinical profileof thesernpatients. Retinoblastoma is discussed in further detail.rnMethod: In a retrospective cross sectional studyconducted in a period of 3 years fromrnFebruary 2017 to January 2020 G.C, The medical records of all pediatric patients with orbitalrntumors evaluated at TASH oncology unit were reviewed.All Patients with initial pretreatmentrncross sectional imaging study and histopathologic analysis and patients who werernconservatively treated for retinoblastoma with diagnosis established through evaluation underrngeneral anesthesiawere included in the study.rnDatawascollectedusingapreparedchecklistandenteredusingMicrosoftexcelsoftwareandlatertranrnsferredtoSPSSversion 20 foranalysis.rnResult:Malignant tumors represented 96.1% of the total 101 cases in our series. The mostrncommon origin of orbital tumor was secondaryextension(69.6%) followed by primary orbitalrntumors 11(16.6%) and metastasis 9(13.6%).The most common primary oculo-orbital tumorrnwas retinoblastoma followed by RMS and optic glioma. Neuroblastoma and leukemiawerernthe most common origins of orbital metastasis. The patients commonly presentedrnwithproptosis(78%)followed by leukocorea(16%). There was correlation between imagingrnand histologic finding in 89.7% of the oculo-orbital tumors in our study. The highestrnconcordance rate was seen for retinoblastoma and optic glioma. The most common orbitalrnsubspace involved was the intraconal site. Patients with retinoblastoma commonly presentedrnat an advanced stage with orbital and intracranial extension.rnConclusion: Pediatric orbital tumors are diagnosed at an advanced stage in our setup withrngrave complications which can be attributed to the late presentation from the parents’ sidernand late referral from the primary care physicians. Thus, it is utmost importance to creaternawareness within the health care workers and the society at large for early detection with canrnsalvage the vision and the life of this patients. Imaging plays an important role in therndiagnosis and management of patients with oculo-orbital tumor. Communication betweenrnradiologist, pathologist and treating ophthalmologist is important in reaching the finalrndiagnosis and for a better outcome in these patients.

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Imaging And Histopathologic Correlation Of Pediatricoculo- Orbital Tumors Evaluated In A Tertiary Level Teaching Hospital In Ethiopia Three Years Retrospective Study

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