The oral nature of indigenous herbal medicinal knowledge and practice poses a challengernthat the knowledge is at risk of extinction after some generations unless otherwiserndocumented. The aim of the present study was to investigate and document the indigenousrnknowledge of herbal medicine and healing practice among the Gamo people in Dorze dere,rnsouthern Ethiopia. Secondary data were reviewed for conceptual framework. The primaryrndata were gathered through in-depth interview, focus group discussion and observation.rnFieldwork was conducted between February and March, 2016. The data were thematicallyrnorganized and analyzed through systematic interpretation. The findings of this study revealedrnthat herbal medicinal practitioners in Dorze were both males and females. The indigenousrnknowledge is acquired either from the herbalist parent or from other places by providingrngifts. The knowledge is transferred through orally either to the family members or trustedrnperson that heir herbal medicinal knowledge based on good personality and dedication tornserve the community. Medicinal plant collection, drug preparation, preservation, andrnprescription are directed by the local culture in which the efficacy of medicines is believed tornbe the result of the natural content of the plants. The herbal medicine and healing is broad inrnscope in the study area which is practiced for healthcare and healing for illnesses of natural,rnsupernatural, and personal etiology. Both the indigenous herbal medicine and the biomedicalrnhealing systems exist together and shifts from one healthcare option to the other and resortsrnare common among the community. There was no interaction between herbalists and thernbiomedical workers. In general, indigenous herbal medicine in Dorze occupies major place asrnpart of their cultural beliefs and practices.rnKeywords/phrases: Dorze, Gamo people, healing, indigenous herbal medicine, indigenous knowledge