This study investigated knowledge, attitude and behavior on HIV/AIDS among blind and deaf students in primaryrnschool of Addis Abeba City administration. Eighty-Four respondents participated in the study. The research adoptedrna descriptive survey research design. Eighty-Four students (40 blind and 44 deaf) participated in the study. Fourrnhypotheses were postulated and tested. The main instrument use to gather data was HIV/AIDS Education inventoryrnwith reliability coefficient of 0.83. Student t-test methods at alpha level of 0.05 were used to analyze the datarncollected. The findings revealed that there were no significant differences in knowledge and behavior aboutrnHIV/AIDS prevention on blind and deaf students. On the basis of the positive outcome, the study furtherrnrecommended some ways of improving the effectiveness of HIV/AIDS Education to be able to achieve the desiredrnresult among blind and deaf students