Modern codes for earthquake resistant building design require consideration of the so-calledrnaccidental design eccentricity, to account for torsional response caused by several factors notrnexplicitly considered in design. This provision requires that the mass centers in the buildingrnfloor be moved a certain percentage of the building‟s dimension (usually 5%) along both thernx and y axes and in both positive and negative directions. rnThis thesis addresses the influence of infill wall on the response of building structuresrnsubjected to earthquake ground motions. Furthermore, the increase an equivalent additionalrneccentricity due to the action of infill wall is estimated. For this purpose, G+10 ReinforcedrnConcrete (RC) models with infill wall type HCB A are used in the study. To study the effectrnof infill materials on accidental eccentricity, Response spectrum analysis performed usingrnETABS 2017 on a set of three-dimensional reinforced concrete multi-story buildings withrnirregular arrangement of infill wall. The obtained results shows The estimated equivalentrnadditional eccentricity of the studied cases exceeded the value of 5% of the dimension rnof the floor (D) perpendicular to the excitation axis which is recommended by several seismicrncode as an accidental eccentricity.