The main purpose of this study was to assess the psychosocial experiences ofrnpodoconiosis patients. To this end, the study examined the psychosocial experiences ofrn120 podoconiosis patients of which 12 purposively selected podoconiosis patientsrnparticipated in the in-depth interview. Each patient's were selected from patient registerrndocwnent by using systematic sampling. The instruments employed in the study wererninterviewer administrated questionnaire and semi structured interview. The questionnairernincludes Rosenberg Self-Esteem scale, SRQ20, and Likert scale type questions developedrnby the researcher. Methods of data analysis employed in the study were descriptivernstatistics, bivariate correlations, one way ANOV A and multiple regressions. The resultsrnof quantitative and qualitative analyses of the data disclosed that podoconiosis patientsrnexperience negative social experience like displacement, interpersonal relationshiprnproblems, marriage problem, decision making problem. The patients have low selfesteemrnand high mental distress. Males experience more negative social experience andrnhigh mental distress than females, and the older age group patients' experience lessrnnegative social experience and mental di stress than younger podoconiosis patients. Thernself-esteem of the patients decreases when their educational status increases whereasrnmental distress decreases with increasing education level. When the severity level of thernpatients increases their negative social experience and mental distress increases. Sex andrnseverity level have positive correlation with social experience and mental distressrnwhereas age of the patients is negatively correlated with the social experience and mentalrndistress. Physical disability, economic challenge, absence of counseling service, badrnsmell of the leg, societal negative reactions were the major problems which hinderrnpodoconiosis patients to integrate into the wider community. Performing religious rituals,rndiscussing with family, friends and relatives, and aggressive way of acting are some ofrnthe coping strategies used by the patients to manage their stress. On the basis of thernfindings the study finally provided discussions. Providing counseling service forrnpodoconiosis patients, integrating the disease into the health care system of the country,rnand civil societies and professionals should play their part to address the psychosocialrnproblems of podoconiosis patients are among the reconmlendations provided based onrnthe study.