Methicillin Resistance Profile Of Staphylococcusaureus Isolated From Burn Wound Patients In Selected Hospitals In Zaria Nigeria

Antimicrobial resistance is a persistent problem where antibiotics are abused or misused. The work determined the methicillin resistance profile of Staphylococcus aureus isolated from burn wound patients in selected hospitals in Zaria, Nigeria. A total of 160 burn wound swabs were obtained from patients and inoculated on Mannitol Salt Agar (MSA) medium. Twelve (12) Staphylococcus aureusisolates were biochemically characterized. Antibiotic susceptibility testing was carried out on all the isolates by disk diffusion method. All the isolates were resistant to at least 2 out of 8 antibiotics tested. The resistancepattern of the isolates was:Cefoxitin(100%),Oxacillin(83.33%),Tetracycline(75%), Vancomycin(75%),Ciprofloxacin(66.7%),Erythromycin(66.7), Gentamicin(41.7%) andChloramphenicol(25%). The Multiple Antibiotic Resistance Index was between 0.25-1.00. Out of the 12 Staphylococcus aureus isolates 9 were methicillin resistant as detected using PBP latex agglutination test kit. It is important that hospitals should monitor Staphylococcusaureus infection in patients with burn wound so as to facilitate management and treatment of the burn wound

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