Comparative Study On Pathological Changes In Sheep And Goats Experimentally Infected With Haemonchus Contortus

The experimental study was done between October, 2019 and June, 2020 in the fly-proof experimental animal facility located in the premise of the college of veterinary medicine and Agriculture at Bishoftu. A total of 14 male goat (G1 and G2) and 14 male sheep (G3 and G4) were allotted in to four equal groups. Single dose of 10,000 of infective larvae of Haemonchus contortus (L3) was orally administered to each animal in G1 and G3. Parameters such as body weight, PCV, haemoglobin, worm count, serum total protein, serum albumin, alkaline phosphatase and aspartate aminotransferase were measured. Moreover, histopathological sections were stained and examined for general changes as well as for changes in specific cells such as tissue eosinophilia and parietal cell population. The findings show that 1) All infected sheep and goats developed the infection with higher mean worm burden in goats (5590) than sheep (2887) and the difference was significant (P

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