A study was conducted to determine the prevalence of ectoparasites and associated gross andrnmicroscopic skin lesions in sheep and goats in Kamba and Bonke districts (woredas) of Gamo-rnGofa Zone in Southern Naions Nationalities and peoples Regional State. The study was conducted from October 2007 to April 2008. During the study period a total of 483 sheep and 503 goats were examined for the presence of ectoparasites and lesions caused by these parasites.rnStudy sheep and goats were randomly selected from fifteen peasants associations of Kamba and Bonke districts. An overall prevalence of (73.53%) of ectoparasites was recorded in both host species