Background: Intestinal Parasites which consist of protozoa and helminths mostly infect gastro-intestinal tract of humans. Infections are widely distributed in tropical and sub-tropical area with greatest number of occurrence in sub-sahara Africa, China and Asia. In Ethiopia high infection rate of intestinal parasites is attributing to factors associated with low socio-economic status such as, poor personal hygiene, environmental sanitation, and low household income, poor access to health services, overcrowding and lack of clean water supplies. rnObjective: to assess the major intestinal parasite species and determine their Infection rate in children less than five years of age in Addis Ketema Sub-City Health Canter, Addis Ababa during Sept. 2017-May. 2018. rnMethod: A cross sectional study was conducted on major intestinal parasite species in children under-five years of age in Addis Ketema Sub-City Health Canter during Sept. 2017- May 2018. Stool samples (n=384) were collected, 45.8% from males and 54.2% from females and examined for intestinal parasites using wet mount and formol-ether concentration methods. In addition, a total of 384 parents and caregiver of under-five children were interviewed regarding their Knowledge, attitude and practice about intestinal parasitic infections. Data were analyzed using SPSS version 20.0 statistical software and P values were used to check the presence of association between dependent and independent variables. P