Postgraduate Project Topics, Thesis and Dissertation
9621. Physico-chemical Characterization Of Native And Microcrystalline Cellulose From Sugarcane Bagasse And Evaluation Of The Microcrystalline Cellulose As Directly Compressible Tablet Excipient
Sugarcane bagasse (SCB) is an abundant agricultural lignocellulose byproduct. In this study, cellulose was extracted from SCB by two methods, by acid treatment with or without dewaxing. Microcrystalline cellulose (MCC) was prepared from extracted cellulose by HCl hydrolysis with or without...
9622. Assessment Of The Management Of Dyspepsia In Health Centers Of Addis Ababa City Administration Ethiopia
Despite the progress made in reducing morbidity, dyspepsia is one of the most common GI diseases, resulting in impaired quality of life and work loss. The purpose of this study was to assess the management of dyspepsia in health centers of Addis Ababa city administration. A cross sectional study...
9623. Assessment Of Drug Therapy Problems And Cardiovascular Disease Risk Among Adult Hypertensive Patients At All Africa Leprosy And Tuberculosis Rehabilitation And Training Centre Addis Ababa Ethiopia
Hypertensive patients are at high risk of developing drug therapy problems (DTPs) and poor adherence due to different factors like: presence of comorbidities, polypharmacy and complexity of drug regimens. Occurrences of DTPs in hypertensive patients are associated with harmful health outcomes and...
9624. Evaluation Of Wound Healing Activity Of 80 Methanol Leaf Extract Of Discopodium Penninervium Hochst (solanaceae) In Mice
Discopodium penninervum is among the Ethiopian medicinal plants claimed for wound healingrnactivity. However, to date, there is no scientific report on evaluation of its wound healingrnactivity. Thus, this work was initiated to investigate wound healing activity of 80 % methanolrnleaf extract of...
9625. Isolation And Characterization Of Native Cellulose And Microcrystalline Cellulose From Teff Straw And Evaluation Of Microcrystalline Cellulose As Directly Compressible Pharmaceutical Excipient
Cellulose is one of the major components of agricultural byproducts. Teff is the most widely cultivated cereal crop in Ethiopia covering 22.95% of the cultivated land from which about 7.46 million tons of Teff straw is produced as a byproduct each year. The aim of this study was to isolate and...
9626. Assessment Of Drug Therapy Problems And Medication Adherence Among Ambulatory Hypertensive Patients On Follow Up At Tikur Anbessa Specialized Hospital
Hypertensive patients are at high risk of drug therapy problems (DTPs), as there is multiple drug use for their comorbidities. To date, studies regarding DTPs in hypertensive patients are limited in Ethiopia. Thus, this study aimed to assess DTPs and medication adherence among ambulatory...
9627. Identification Of Anti-leishmanial Leads From Open Access Pathogen Box
Leishmaniasis is a vector-borne disease caused by an obligate intracellular protozoan of the genus Leishmania. The ranges of drugs available to treat this disease are limited; therefore, there is a substantial need to develop new medicines or drug combinations. Aiming to find potential...
9628. Identification And Resolution Of Drug Related Problems In Pediatric Hematologyoncology Ward Of Tikur Anbessa Specialized Hospital Addis Ababa Ethiopia
Even though, medications play a major role in the cure, palliation and inhibition of disease, they also expose patients to drug related problems. Drug related problems are frequent and may result in reduced quality of life, and even morbidity and mortality. Many studies have shown that clinical...
9629. Evaluation Of The Diuretic Activity Of The Aqueous And 80 Methanol Extracts Of The Leaves Of Cucumis Dipsaceus Ehrenb (cuccurbitaceae) In Rats
Diuretics are drugs, which increase the excretion of electrolytes and water from the bodyrnby an action on the kidney. Their primary effect is to decrease the re-absorption of saltrnfrom the filtrate and increase water loss. They are used primarily to prevent and alleviaternfluid overload like...
9630. Evaluation Of Protease Inhibitors Based Anti-retroviral Regimen Induced Liver Injury At Zewditu Memorial Hospital.
Background: The inclusion of protease inhibitors (PIs) in therapeutic regimens has a significantrnimpact on the success of the treatment; these classes have been associated with liver-related injuryrnrnin some individuals. Rates of hepatotoxicity from registration trials of various PIs havernranged...
9631. Antidiarrheal Activity Of The 80 Methanol Root Extract Of Thalictrum Ryhnchocarpum Dill. A. Rich And Its Major Constituent Against Castor Oil- Induced Diarrhea In Mice
Diarrhea is one of the main causes of infant mortality in Ethiopia and in many other developingrncountries, causing about 4 to 8 million deaths annually worldwide. Despite recent reductions inrnmorbidity and mortality worldwide, diarrhea still remains one of the leading causes of death...
9632. Determination Of Efavirenz Based Antiretroviral Therapy Associated Insulin Resistance In Adult Human Immunodeficiency Virus Infected Patients Receiving Antiretroviral Therapy Alone And In Combination With Anti Tuberculosis Dr
The invention of Highly Active Antiretroviral Therapy (HAART) has achromatized the HumanrnImmunodeficiency Virus (HIV) infection from a fatal disease to a chronic condition marked byrnreduced morbidity and mortality. This success in controlling HIV replication and restoring immunityrnhas been...
9633. Evaluation Of Antiproliferative Activity Of The Aerial Part Essential Oil Of Urtica Simenesis Hochst And Hydroalcholic Leaf Extract Of Discopodium Penninervium Hochst.
Cancer is a generic term for a large group of diseases that can affect any part of the body. It is the rnsecond leading cause of death globally and is estimated to account for 9.6 million deaths in 2018. rnCurrently, chemotherapy, radiotherapy and surgical measure are the key tools for cancer...
9634. Medicine Supply Chain Management Practice By Health Extension Workers In Selected Primary Health Care Units In North Shewa Zone Amhara Region Ethiopia A Qualitative Study
Introduction: Health Extension Workers (HEWs) play key roles in the health care system ofrnEthiopia. They do health promotion, prevention and curative activities as well as manage arnnumber of items including medicines at the community and health post level in which access tornhealth care is...
9635. Evaluation Of In Vivo Anti-malarial Activity Of 80 Methanol Extract And Solvent Fractions Of Seeds Of Prunes Persica (l) Bastche Against Plasmodium Berghei In Mice
Malaria continues as major health problem in subtropical region of the world. The resistances ofrnmalaria parasites to available drugs endanger all the good result that has been found. Therefore,rnthe development of novel drug is a must to do job. One of the key sources is traditionalrnmedicinal...
9636. Warehousing And Inventory Management Performance And Associated Factors After Hcmis Implementation In Tikur Anbessa Specialized Hospital
Background:The provision of complete health care necessitates the availability of safe, effectivernand affordable drugs and related supplies of the required quality, in adequate quantity at allrntimes. To meet this need TikurAnbessa Specialized Hospital, Pharmacy Service Directoraternstrives to...
9637. Segmentation Of Sonicated Blood Cells And Ultrasound Contrast Agent Microbubbles From Time-lapse Microscopic Images
Blood cells and ultrasound contrast agent microbubbles behave strangely when subjected tornan ultrasound ï¬eld. They migrate towards the nodes of the ultrasound wave and form circularrnpatterns. However, differentiation between blood cells and ultrasound contrast agentrnmicrobubbles can be...
9638. Design Of Low Cost Temperature Controlled Neonatal Transportation Device
Temperature instability in preterm neonates is one of the major causes of morbidity andrnmortality. The immature systems and organs of preterm neonates in combination with poorrnfacilities and after birth care lead to lifelong health complications, if not death. The drop ofrntemperature in preterm...
9639. Slice Based 3d Cell Segmentation Of Optical Projection Tomography Images
Optical Projection Tomography (OPT) is a new imaging technique used to image cellsrnin 3D cultured in a hydrogel. Reconstructed OPT images of cells suffer from severalrnartifacts. These artifacts reduce the overall image quality. This will create a challengernfor isolating and studying each...
9640. Performance Predictive Model Of Esb As Service Integration Grows The Case Of Ethio Telecom
Service Oriented Architecture (SOA) is an architectural pattern that is based on the concept of arnservice and addresses, the requirements of loosely coupled, and protocol independent distributedrncomputing. SOA used enterprise Service Bus (ESB) to realize its principles. ESB is an...
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